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KMID : 0545120140240111592
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Journal of Microbiology and Biotechnology
2014 Volume.24 No. 11 p.1592 ~ p.1596
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Lactobacillus brevis G101 Inhibits the Absorption of Monosodium Glutamate in Mice
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Jang Se-Eun
Han Myung-Joo
Kim Se-Young
Kim Dong-Hyun
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Abstract
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To evaluate the effect of Lactobacillus brevis G-101 on absorption of monosodium glutamate (MSG), we orally administered MSG with or without G-101 in mice and measured the maximum concentration (Cmax) and blood concentration curve (AUC) of MSG and γ- aminobutyric acid (GABA). Oral administration of G-101 (1 × 109 CFU/mouse) potently inhibited Cmax and AUC of MSG by 97.8% and 94.3%, respectively (p < 0.05), but increased those of GABA by 32.1% and 67.7%, respectively (p < 0.05). G-101 inhibited the absorption of MSG. These results suggest that G-101 may reduce the side effect of MSG by inhibiting the absorption of MSG.
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KEYWORD
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Lactobacillus plantarum G-101, monosodium glutamate, γ-aminobutyric acid, absorption
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